Uji Aktivitas Antijamur Fraksi Etanol Rimpang Temu Kunci (Boesenbergia pandurata (Roxb.) Schlecht) Terhadap Candida albicans dan Trichophyton mentagrophytes Beserta Profil Kromatografi Lapis Tipisnya

Abstrak

In Indonesia, skin and nail diseases due to fungal infection is still prevalent, especially because the air is humid and hot, less of the

In Indonesia, skin and nail diseases due to fungal infection is still prevalent, especially because the air is humid and hot, less of the levels of health and poor environmental sanitation. Among the diseases caused   by   Candida   albicans   and   Trichophyton   mentagrophytes.

On the other hand some plants from the Zingiberaceae, among the plants temu ireng, turmeric, temu giring, and temu lawak has been demonstrated  to  have  antifungal  activity  by  previous  researchers. Temu kunci is one of the plants from the Zingberaceae, for it has done the research activities of temu kunci ethanol fraction (Boesenbergia pandurata (Roxb.) Schlecht) of the fungus Candida albicans and Trichophyton  mentagrophytes.  Antifungal  activity  assays  performed with solid dilution method.

The  results  showed  that  Minimal  Bacterisid  Concentration (MBC) of the temu kunci ethanol fraction to the growth of the fungus Candida albicans and Trichophyton mentagrophytes are the same is 4%. Thin Layer Chromatography test for examining the content of the compound in plants using a mobile phase of ethyl acetate: benzene petroletum (9:11) with vanillin spray reagent-phase sulfuric acid and ethyl acetate: methanol: water (100:13,5:10) with reagents sitroborat spray  and  NH3   vapor.  Profile kromatrogram  temu  kunci  ethanol fractions showed that fractions containing compounds group terpenoids and flavonoids.